ea0028p21 | Bone | SFEBES2012
Lim Yuen Han
, Pattman Stewart
, Guadagno Joe
, Duddy Martin
, Smith Gillian
, Wilkinson Carmel
, Quinton Richard
Background: Multiple sclerosis (MS) is associated with low ambient ultraviolet B (UVB) light in childhood and in utero (relative risk of developing MS is 1.2 for those born in spring). Besides, the MS-linked HLA-DRB1 allele interacts strongly with vitamin D in vitro, and vitamin D levels are lower in MS patients. Fatigue and musculoskeletal aches/pains are prominent symptoms in both MS and vitamin D deficiency. Moreover, having any chronic disease may predispose to stay...